People have been using a variety of products for pleasurable sexual experiences and stay longer in bed. However, taking desperate measures like mixing Cocaine with Cialis for longer erections can do more harm than good!
Can You Mix Cialis With Cocaine?
Cialis is a phosphodiesterase-5 inhibitor used for effective treatment of erectile dysfunction (ED). However, some recreational drug users combine Cialis and Cocaine for a multiplier effect.
Although such combinations provide temporary satisfaction, they might result in life-threatening complications in some cases. However, before answering, “Can you take Cialis with Cocaine?” let’s understand the basics of these two drugs.
What Is Cialis?
Cialis is a brand name for Tadafil, the most versatile phosphodiesterase-5 (PDE5) inhibitor, used to treat ED, Symptomatic Benign Prostatic Hyperplasia, and Pulmonary Arterial Hypertension. It has a long half-life of 17.5 hours (1).
Inadequate penile perfusion is one of the primary etiologies of ED. Cialis inhibits PDE5 enzyme in the penile erectile tissue, corpora cavernosa, increasing blood flow to the penis. Consequently, the penis fills up like a balloon, gets erect, and “appears” enlarged. However, it takes almost 30 minutes for the drug to produce visible effects.
Cialis tablets are available in doses of 5mg, 10 mg, and 20 mg. The individual dose is adjusted according to efficacy and tolerability (2).
What Is Cocaine?
Cocaine is an anesthetic, a powerful stimulant, and a drug of abuse. It causes anesthesia and vasoconstriction in the mucosa. However, cocaine has high systemic absorption resulting in adverse cardiovascular effects (3).
When taken before the sexual activity, cocaine causes excessive release of dopamine and produces feelings of motivation, euphoria, and concentration. Cocaine adds endurance and pleasure to the sex, helping achieve enjoyable orgasms.
Mixing Cocaine and Cialis
Many people mix Cialis with stimulants like cocaine to produce “sextasy.” However, doctors discourage the combined intake of Cialis and Cocaine for several reasons.
Cardiovascular problems
Cocaine is a vasoconstrictor that reduces blood flow to the organs, including the heart. Reduced blood flow leads to inadequate oxygen supply to the heart, increasing the risk of irregular heartbeat, angina, and stroke (4).
Cialis produces effects opposite to that of cocaine. It causes vasodilation, increasing blood flow (5).
Since both Cialis and Cocaine have opposing effects, they can produce unpredictable blood pressure changes, damaging the blood vessels.
Serotonin Syndrome
Combining Cocaine with Cialis can cause an abnormal rise in serotonin levels producing a life-threatening complication ‘Serotonin Syndrome”. It is characterized by increased sweating, muscle rigidity, restlessness, agitation, hypertension, and tachycardia. High-grade fever, seizures, and irregular heartbeat also occur in severe Serotonin Syndrome (6).
Priapism
Priapism is another complication of combined use of Cialis with Cocaine. In priapism, the penis gets painfully engorged for several hours in the absence of any sexual stimulation. The erection does not settle without medical intervention. It is a medical emergency that can damage the penis and bladder (7).
Rapid Decline in Blood pressure
One should never take Cialis with nitrates because of the vasodilating effect of both. When cocaine, cut with nitrates, is mixed with Cialis, it can cause excessive vasodilation resulting in abnormal fall in blood pressure, heart attack, and stroke (8).
Psychological Dependence
In addition to physiological complications, the combined use of Cialis and Cocaine has psychological effects too. Psychological dependence on the use of Cialis and Cocaine for satisfactory sexual performance is one of the major risks. Therefore, one would need to take with Cialis and Cocaine to perform sexually and obtain pleasure.
Can We Treat ED With the Combination of Cialis and Cocaine?
As already discussed, both Cialis and Cocaine have different mechanisms of action. Cialis causes vasodilation, but cocaine causes vasoconstriction. Therefore, cocaine reduces the efficacy of the vasodilatory effects of Cialis. Thus, the combined use of both drugs for the treatment of ED is not recommended.
Conclusion
Cialis is a prescription drug, used legally to treat a prevalent condition “Erectile Dysfunction.” In comparison, cocaine is an illegal drug with several associated health risks, including addiction and dependence.
Although cocaine is a stimulant, mixing it with Cialis will do more harm to sexual performance than good. Therefore, is someone asks you, “Can we mix Cocaine with Cialis” your answer should be a straightforward” No”!
